Endocrine Abstracts

IntroductionThyrotoxicosis due to functioning metastases in differentiated thyroid cancer (DTC) is exceedingly rare. The mechanism remains unknown despite several hypotheses. We report on a case of transient thyrotoxicosis due to functioning bone metastasis of follicular thyroid carcinoma.Case reportWe present a case of female patient of 68-years-old diagnosed with follicular thyroid carcinoma revealed by a l...

IntroductionRadioiodine I-131 (RAI) therapy of Graves’ Disease (GD) affects biological thyroid function, clinical signs of hyperthyroidism (SCH), but also the mass of the thyroid (MT). The aim of our study is to assess the effect of RAI on GD and TM according to biological thyroid function after 6 and 12 months.MethodsThis is a prospective study of 86 patients (mean age 43 ± 11, sex ratio 2.07) refe...

Introduction: Hypoparathyroidism (HypoPT) is a rare endocrine disease characterized by abnormally low concentrations of PTH resulting in hypocalcemia. Etiologies are various and are dominated by postoperative HypoPT. HypoPT needs a lifelong treatment and follow-up in order to maintain appropriate calcium levels and prevent chronic complications.Patients and Methods: A retrospective descriptive study was conducted at the endocrinology department in Fattou...

Introduction : Primary adrenal lymphomas (PAL) are extremely rare and constitute 0.5% of all adrenal tumors. The number of cases described is approximately 70 cases [1] and It is bilaterally manifested in approximately 70% of cases [2]. The diagnosis is made on histological features, as there is no specific symptoms. Treatement is based on chemotherapy and prognosis is usually poor. We report two cases of bilateral PAL.Cases: First case: A 63-year-old wo...

Introduction: Congenital adrenal hyperplasia (CAH) is a group of autosomal recessive disorders that result from the deficiency of one of several enzymes involved in the steroidogenic pathway for cortisol biosynthesis. The most common cause of CAH, accounting for 90% of cases, is 21-hydroxylase deficiency. The symptoms of disease very depending on the nature and severity of the enzyme deficiency as well as the sex of the individual. Non-classical CAH is generally late onset. Ho...

Introduction: Central diabetes insipidus (CDI) is a heterogeneous condition characterized by the presence of polyuria and polydipsia due to a deficiency of arginine vasopressin. Frequently, CDI is wrongly considered idiopathic if not associated with other signs and symptoms.Case report: We report the case of a 50-year-old woman diagnosed with idiopathic central diabetes insipidus at the age of 34. The MRI scan of the hypothalamus and pituitary gland was ...

IntroductionSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel coronavirus that caused a global pandemic in 2020. The virus has infected more than 100 million people worldwide and the pandemic is still spreading. It can affect practically all organs. Data on the impact of SARSCoV-2 on the thyroid gland are very scarce. Two patients with Graves’ disease (GD) and COVID-19 have been recently published(1). We present a case GD occur...